BDBM50346961 CHEMBL1795875

SMILES CN1CCC(CC1)NC(=O)c1ccc(cc1)-c1ccc(cc1C(F)(F)F)-n1c2c(ccc1=O)cnc1ccc(cc21)-c1cnc2ccccc2c1

InChI Key InChIKey=YACAVUFIAWVHTR-UHFFFAOYSA-N

Data  9 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50346961   

LigandPNGBDBM50346961(CHEMBL1795875)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of P110delta/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50346961(CHEMBL1795875)
Affinity DataIC50: 922nMAssay Description:Inhibition of P110alpha/p85alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Mouse)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50346961(CHEMBL1795875)
Affinity DataEC50:  5nMAssay Description:Inhibition of mTOR-dependent S6K phosphorylation at T389 residue in MEF cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase alpha(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50346961(CHEMBL1795875)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI4K alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 4-kinase beta(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50346961(CHEMBL1795875)
Affinity DataIC50: 3.44E+3nMAssay Description:Inhibition of PI4K betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50346961(CHEMBL1795875)
Affinity DataIC50: 1.11E+3nMAssay Description:Inhibition of PI3K C2alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50346961(CHEMBL1795875)
Affinity DataIC50: 437nMAssay Description:Inhibition of PI3K C2betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetPhosphatidylinositol 3-kinase catalytic subunit type 3(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50346961(CHEMBL1795875)
Affinity DataIC50: 170nMAssay Description:Inhibition of human VPS34More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50346961(CHEMBL1795875)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of P110gammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50346961(CHEMBL1795875)
Affinity DataIC50: 3nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed