BDBM50346613 CHEMBL470029::Oleanonic Acid

SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CCC(=O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]2C1)C(O)=O

InChI Key InChIKey=FMIMFCRXYXVFTA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50346613   

TargetGlycogen phosphorylase, muscle form(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346613(Oleanonic Acid | CHEMBL470029)
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of rabbit muscle GPaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/7/2012
Entry Details Article
PubMed
TargetGlycogen phosphorylase, muscle form(Rabbit)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346613(Oleanonic Acid | CHEMBL470029)
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylase A assessed as release of phosphate from glucose-1-phosphate after 25 mins by microplate reader bas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Dartmouth College

Curated by ChEMBL
LigandPNGBDBM50346613(Oleanonic Acid | CHEMBL470029)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of inducible nitric oxide synthase in activated macrophagesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/2/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50346613(Oleanonic Acid | CHEMBL470029)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human recombinant PTP1B after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/19/2012
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346613(Oleanonic Acid | CHEMBL470029)
Affinity DataIC50: 0.221nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50346613(Oleanonic Acid | CHEMBL470029)
Affinity DataIC50: 5.32E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chosun University

Curated by ChEMBL
LigandPNGBDBM50346613(Oleanonic Acid | CHEMBL470029)
Affinity DataIC50: 5.32E+3nMAssay Description:Inhibition of PTP1B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2020
Entry Details Article

TargetPancreatic triacylglycerol lipase(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50346613(Oleanonic Acid | CHEMBL470029)
Affinity DataIC50: 490nMAssay Description:Inhibition of Pancreatic lipase (unknown origin) using 4-MUO as fluorescent substrate preincubated for 3 mins followed by substrate addition measured...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed