BDBM50346551 CHEMBL1795371

SMILES O=[#6]1-[#7]-[#6](=S)-[#7]-[#6](=O)\[#6]-1=[#6]/c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=SJEJSSJFCUVOHA-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50346551   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50346551(CHEMBL1795371)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human Sirt2More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Guru Jambheshwar University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50346551(CHEMBL1795371)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of recombinant human SIRT1 assessed as inhibition of deacetylase activity using ZMAL as substrate measured after 4 hrs by Fluor de Lys ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50346551(CHEMBL1795371)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human N-terminal 6His-tagged SIRT2 assessed as inhibition of deacetylase activity using ZMAL as substrate measured after 4 hrs by Fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/2/2018
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50346551(CHEMBL1795371)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of recombinant SIRT2 using ZMAL substrate after 4 hrs by homogeneous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50346551(CHEMBL1795371)
Affinity DataIC50: 4.03E+4nMAssay Description:Inhibition of recombinant SIRT3 using ZMAL substrate after 4 hrs by homogeneous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50346551(CHEMBL1795371)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of SIRT5 using ZK(suc)A substrate after 1 hr by homogeneous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Guru Jambheshwar University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50346551(CHEMBL1795371)
Affinity DataIC50: 5.05E+4nMAssay Description:Inhibition of recombinant SIRT1 using ZMAL substrate after 4 hrs by homogeneous fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Guru Jambheshwar University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50346551(CHEMBL1795371)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of sirtuin 1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Martin-Luther University of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50346551(CHEMBL1795371)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of sirtuin 2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed