BDBM50346378 CHEMBL1783353::N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)propyl)picolinamidine

SMILES N#CNC(=NCCCN1CCN(CC1)c1cccc2ccccc12)c1ccccn1

InChI Key InChIKey=YWTAKDXVVAFCSC-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50346378   

Target5-hydroxytryptamine receptor 1A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346378(N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  5.85nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex homogenates after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346378(N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi:  224nMAssay Description:Displacement of [3H]Ketanserin from 5HT2A receptor in Sprague-Dawley rat frontal cortical homogenates after 15 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346378(N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]spiperone from dopamine D2 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Rat)
University of Naples Federico II

Curated by ChEMBL
LigandPNGBDBM50346378(N'-cyano-N-(3-(4-(naphthalen-1-yl)piperazin-1-yl)p...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH 23390 from dopamine D1 receptor in rat corpora striatum homogenates after 15 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed