BDBM50346320 (S)-3-(3-hydroxy-4-(4-(1,4,5,6-tetrahydropyrimidin-2-ylamino)piperidin-1-yl)benzamido)-2-(4-hydroxyphenylsulfonamido)propanoic acid::CHEMBL1782659

SMILES [#8]-[#6](=O)-[#6@H](-[#6]-[#7]-[#6](=O)-c1ccc(-[#7]-2-[#6]-[#6]-[#6](-[#6]-[#6]-2)\[#7]=[#6]-2\[#7]-[#6]-[#6]-[#6]-[#7]-2)c(-[#8])c1)-[#7]S(=O)(=O)c1ccc(-[#8])cc1

InChI Key InChIKey=NTUOURDYBNNAAG-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50346320   

TargetIntegrin alpha-V/beta-3(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50346320((S)-3-(3-hydroxy-4-(4-(1,4,5,6-tetrahydropyrimidin...)
Affinity DataIC50: 390nMAssay Description:Antagonist activity at alphavbeta3 integrin receptor human VSMC assessed as inhibition of vitronectin-induced cell adhesionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetIntegrin alpha-IIb/beta-3(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50346320((S)-3-(3-hydroxy-4-(4-(1,4,5,6-tetrahydropyrimidin...)
Affinity DataIC50: 0.940nMAssay Description:Antagonist activity at alpha2bbeta3 integrin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50346320((S)-3-(3-hydroxy-4-(4-(1,4,5,6-tetrahydropyrimidin...)
Affinity DataIC50: 0.300nMAssay Description:Antagonist activity at alphavbeta3 integrin receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed