BDBM50346282 CHEMBL1782555::sodium(3R,5R)-7-(5-cyclopropyl-2-(4-fluorophenyl)-4-(4-methoxybenzylcarbamoyl)-1H-imidazol-1-yl)-3,5-dihydroxyheptanoate

SMILES COc1ccc(CNC(=O)c2nc(-c3ccc(F)cc3)n(CC[C@@H](O)C[C@@H](O)CC([O-])=O)c2C2CC2)cc1

InChI Key InChIKey=KXFWXSJMVLPHDA-UHFFFAOYSA-M

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50346282   

LigandPNGBDBM50346282(sodium(3R,5R)-7-(5-cyclopropyl-2-(4-fluorophenyl)-...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of HMG-CoA reductase in Sprague-Dawley rat liver microsomes using [14C]HMG-CoA as substrate preincubated for 0.5 hrs before substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2011
Entry Details Article
PubMed