BDBM50346158 5-(2-(3-(1H-pyrrol-1-yl)propoxy)-4-methoxyphenyl)-3-phenylisoxazole::CHEMBL1783782

SMILES COc1ccc(-c2cc(no2)-c2ccccc2)c(OCCCN2CCCC2)c1

InChI Key InChIKey=PNCFZTDLKBLHJY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50346158   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50346158(5-(2-(3-(1H-pyrrol-1-yl)propoxy)-4-methoxyphenyl)-...)
Affinity DataIC50: 3.46E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in presence of 0.01% Triton X-100 by modified Golds...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Central Drug Research Institute

Curated by ChEMBL
LigandPNGBDBM50346158(5-(2-(3-(1H-pyrrol-1-yl)propoxy)-4-methoxyphenyl)-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of protein tyrosine phosphatase-1B at 10 uM incubated for 10 mins using pNPP substrate in absence of Triton X-100 by modified Goldstein me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed