BDBM50346117 2-(4-(5-allyl-6-methyl-2-(5-methylthiophen-2-yl)pyrimidin-4-ylamino)phenyl)acetic acid::CHEMBL1782286

SMILES Cc1ccc(s1)-c1nc(C)c(CC=C)c(Nc2ccc(CC(O)=O)cc2)n1

InChI Key InChIKey=NPNUFIXGALUZRZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50346117   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50346117(2-(4-(5-allyl-6-methyl-2-(5-methylthiophen-2-yl)py...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50346117(2-(4-(5-allyl-6-methyl-2-(5-methylthiophen-2-yl)py...)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human PDE4D3 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed