BDBM50346108 4-(5-allyl-6-methyl-2-p-tolylpyrimidin-4-ylamino)benzoic acid::CHEMBL1782294

SMILES Cc1ccc(cc1)-c1nc(C)c(CC=C)c(Nc2ccc(cc2)C(O)=O)n1

InChI Key InChIKey=HTOSQCGNJVWEKE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50346108   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50346108(4-(5-allyl-6-methyl-2-p-tolylpyrimidin-4-ylamino)b...)
Affinity DataIC50: 220nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50346108(4-(5-allyl-6-methyl-2-p-tolylpyrimidin-4-ylamino)b...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human PDE4D3 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed