BDBM50346103 4-(5-allyl-6-methyl-2-(thiophen-2-yl)pyrimidin-4-ylamino)benzoic acid::CHEMBL1782289

SMILES Cc1nc(nc(Nc2ccc(cc2)C(O)=O)c1CC=C)-c1cccs1

InChI Key InChIKey=SYBOCZJFEMYMOY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50346103   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50346103(4-(5-allyl-6-methyl-2-(thiophen-2-yl)pyrimidin-4-y...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human PDE4B1 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
Asahi Kasei Pharma

Curated by ChEMBL
LigandPNGBDBM50346103(4-(5-allyl-6-methyl-2-(thiophen-2-yl)pyrimidin-4-y...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human PDE4D3 incubated for 10 mins using cAMP and [3H]cAMP substratesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed