BDBM50345981 3-(1-methylpiperidin-4-yl)-5-(naphthalen-2-ylsulfonyl)-1H-indazole::CHEMBL1783608

SMILES CN1CCC(CC1)c1n[nH]c2ccc(cc12)S(=O)(=O)c1ccc2ccccc2c1

InChI Key InChIKey=BJLXTIRVHASGOE-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345981   

Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50345981(3-(1-methylpiperidin-4-yl)-5-(naphthalen-2-ylsulfo...)
Affinity DataIC50: 102nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in HeLa cells assessed as inhibition of 5-HT-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50345981(3-(1-methylpiperidin-4-yl)-5-(naphthalen-2-ylsulfo...)
Affinity DataKi:  9.60nMAssay Description:Displacement of [3H]LSD from human 5HT6 receptor expressed in HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed