BDBM50345952 3-(4-Chloro-phenyl)-9-(methyl-prop-2-ynyl-amino)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one::CHEMBL1784051

SMILES CN(CC#C)c1ccnc2sc3c(ncn(-c4ccc(Cl)cc4)c3=O)c12

InChI Key InChIKey=ZYBBFXGBKSOYGP-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50345952   

TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345952(3-(4-Chloro-phenyl)-9-(methyl-prop-2-ynyl-amino)-3...)
Affinity DataIC50: 3.80nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345952(3-(4-Chloro-phenyl)-9-(methyl-prop-2-ynyl-amino)-3...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345952(3-(4-Chloro-phenyl)-9-(methyl-prop-2-ynyl-amino)-3...)
Affinity DataKi:  18nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed