BDBM50345944 3-(3-Fluoro-4-methoxy-phenyl)-9-(2-methyl-allylamino)-3H-pyrido[3',2':4,5]thieno[3,2-d]pyrimidin-4-one::CHEMBL1783871

SMILES COc1ccc(cc1F)-n1cnc2c(sc3nccc(NCC(C)=C)c23)c1=O

InChI Key InChIKey=WMYDDNATIVVRLS-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50345944   

TargetMetabotropic glutamate receptor 1(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345944(3-(3-Fluoro-4-methoxy-phenyl)-9-(2-methyl-allylami...)
Affinity DataIC50: 103nMAssay Description:Antagonist activity at human mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345944(3-(3-Fluoro-4-methoxy-phenyl)-9-(2-methyl-allylami...)
Affinity DataIC50: 3.00E+3nMAssay Description:Antagonist activity at human mGluR5More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 1(Rat)
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50345944(3-(3-Fluoro-4-methoxy-phenyl)-9-(2-methyl-allylami...)
Affinity DataKi:  13nMAssay Description:Antagonist activity at rat mGluR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed