BDBM50345569 3-(2-(pyridin-2-yl)ethynyl)-5-nitrobenzonitrile::CHEMBL1784615

SMILES [O-][N+](=O)c1cc(cc(c1)C#Cc1ccccn1)C#N

InChI Key InChIKey=SCEZDEAWHINYOD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50345569   

TargetMetabotropic glutamate receptor 5(Rat)
Institute For Neurodegenerative Disorders

Curated by ChEMBL
LigandPNGBDBM50345569(3-(2-(pyridin-2-yl)ethynyl)-5-nitrobenzonitrile | ...)
Affinity DataIC50: 1.32nMAssay Description:Antagonist activity at rat mGluR5 expressed in human HEK-293 cells assessed as inhibition of glutamate-induced intracellular calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed