BDBM50345276 CHEMBL1784230::Ethyl 5-chloro-6-(4-{[(4-methylbenzyl)amino]carbonyl}piperazin-1-yl)nicotinate

SMILES CCOC(=O)c1cnc(N2CCN(CC2)C(=O)NCc2ccc(C)cc2)c(Cl)c1

InChI Key InChIKey=AEQOMJOKGSDYGH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345276   

TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50345276(Ethyl 5-chloro-6-(4-{[(4-methylbenzyl)amino]carbon...)
Affinity DataIC50: 970nMAssay Description:Displacement of [125I]-AZ11931285 from human recombinant P2Y12 receptor expressed in platelet cell membrane after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetP2Y purinoceptor 12(Human)
Astrazeneca R&D

Curated by ChEMBL
LigandPNGBDBM50345276(Ethyl 5-chloro-6-(4-{[(4-methylbenzyl)amino]carbon...)
Affinity DataIC50: 460nMAssay Description:Antagonist activity at human recombinant P2Y12 receptor expressed in platelet cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed