BDBM50345262 CHEMBL1782533::trans-5-bromo-7-(4-hydroxycyclohexylamino)benzofuran-2-carboxylic acid

SMILES O[C@H]1CC[C@@H](CC1)Nc1cc(Br)cc2cc(oc12)C(O)=O

InChI Key InChIKey=IQNDSBJQOZFMDJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345262   

TargetSerine/threonine-protein kinase pim-1(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50345262(trans-5-bromo-7-(4-hydroxycyclohexylamino)benzofur...)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of human Pim1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 45 mins by off-chip mobility shift methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50345262(trans-5-bromo-7-(4-hydroxycyclohexylamino)benzofur...)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of human Pim2 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 90 mins by off-chip mobility shift methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed