BDBM50345232 5-bromo-7-methoxy-1-benzofuran-2-carboxylic acid::5-bromo-7-methoxybenzofuran-2-carboxylic acid::CHEMBL1738915

SMILES COc1cc(cc2c1oc(c2)C(=O)O)Br

InChI Key InChIKey=OEICZFFUNDGUEF-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50345232   

TargetSerine/threonine-protein kinase pim-1(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50345232(5-bromo-7-methoxy-1-benzofuran-2-carboxylic acid |...)
Affinity DataIC50: 5.80E+3nMAssay Description:Inhibition of human Pim1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 45 mins by off-chip mobility shift methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase pim-1(Human)
Genzyme

Curated by ChEMBL
LigandPNGBDBM50345232(5-bromo-7-methoxy-1-benzofuran-2-carboxylic acid |...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human Pim-1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate preincubated for 15 mins prior substrate addition measured after 45 mins by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)