BDBM50345068 (1,4-diazepan-1-yl)(5-methoxy-1-(4-methoxy-2,3-dimethylphenylsulfonyl)-2-methyl-1H-indol-3-yl)methanone::CHEMBL1779234

SMILES COc1ccc2n(c(C)c(C(=O)N3CCCNCC3)c2c1)S(=O)(=O)c1ccc(OC)c(C)c1C

InChI Key InChIKey=PNQGELHLYTXMRZ-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50345068   

TargetVasopressin V1b receptor(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50345068((1,4-diazepan-1-yl)(5-methoxy-1-(4-methoxy-2,3-dim...)
Affinity DataIC50: 371nMAssay Description:Antagonist activity at human vasopressin V1B receptor expressed in CHO cells assessed as inhibition of AVP-induced calcium mobilisation by luciferase...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetVasopressin V1b receptor(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50345068((1,4-diazepan-1-yl)(5-methoxy-1-(4-methoxy-2,3-dim...)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1B receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetVasopressin V1a receptor(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50345068((1,4-diazepan-1-yl)(5-methoxy-1-(4-methoxy-2,3-dim...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-AVP from human vasopressin V1A receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetVasopressin V2 receptor(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50345068((1,4-diazepan-1-yl)(5-methoxy-1-(4-methoxy-2,3-dim...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-AVP from human vasopressin V2 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetOxytocin receptor(Human)
Msd

Curated by ChEMBL
LigandPNGBDBM50345068((1,4-diazepan-1-yl)(5-methoxy-1-(4-methoxy-2,3-dim...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]oxytocin from human oxytocin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed