BDBM50344894 CHEMBL1780185::ethyl 2-(4-(3-(5,6,7,8-tetrahydronaphthalen-1-yloxy)propoxy)phenylthio)hexanoate

SMILES CCCCC(Sc1ccc(OCCCOc2cccc3CCCCc23)cc1)C(=O)OCC

InChI Key InChIKey=QXGDTPBHDMFVCC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344894   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50344894(ethyl 2-(4-(3-(5,6,7,8-tetrahydronaphthalen-1-ylox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant 5-lipoxygenase expressed in Escherichia coli BL21 assessed as enzyme product formation using arachidonic acid as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Eberhard Karls University Tuebingen

Curated by ChEMBL
LigandPNGBDBM50344894(ethyl 2-(4-(3-(5,6,7,8-tetrahydronaphthalen-1-ylox...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in A23187-stimulated human PMNL assessed as enzyme product formation preincubated 15 mins by RP-HPLC analysis in presenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMed