BDBM50344826 1-(4-chlorobenzyl)-3-hydroxy-3-phenylindolin-2-one::CHEMBL1779927

SMILES OC1(C(=O)N(Cc2ccc(Cl)cc2)c2ccccc12)c1ccccc1

InChI Key InChIKey=SIXPGAYGILPSJO-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50344826   

TargetSodium channel protein type 9 subunit alpha(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50344826(1-(4-chlorobenzyl)-3-hydroxy-3-phenylindolin-2-one...)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of human NaV1.7 expressed in HEK293 cells by [14C]guanidinium influx assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Universidade De £Vora

Curated by ChEMBL
LigandPNGBDBM50344826(1-(4-chlorobenzyl)-3-hydroxy-3-phenylindolin-2-one...)
Affinity DataIC50: 1.02E+3nMAssay Description:Inhibition of equine serum BuChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Universidade De £Vora

Curated by ChEMBL
LigandPNGBDBM50344826(1-(4-chlorobenzyl)-3-hydroxy-3-phenylindolin-2-one...)
Affinity DataIC50: 1.29E+5nMAssay Description:Inhibition of electrophorus electricus AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed