BDBM50344638 2-(3-(2-(5-bromo-2-hydroxybenzoyl)hydrazono)-2-oxoindolin-1-yl)-N-p-tolylacetamide::CHEMBL1779086

SMILES Cc1ccc(NC(=O)CN2C(=O)C(=NNC(=O)c3cc(Br)ccc3O)c3ccccc23)cc1

InChI Key InChIKey=SKLOWEVLEQCOIS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344638   

TargetHepatocyte growth factor receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50344638(2-(3-(2-(5-bromo-2-hydroxybenzoyl)hydrazono)-2-oxo...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of purified c-Met using poly(glu,tyr) as substrate after 60 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetHeparanase(Human)
Centro De Investigaci�N Pr�Ncipe Felipe

Curated by ChEMBL
LigandPNGBDBM50344638(2-(3-(2-(5-bromo-2-hydroxybenzoyl)hydrazono)-2-oxo...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant heparanase catalytic stie (unknown origin) expressed in Escherichia coli BL21 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed