BDBM50344621 (E)-3-(5-Bromo-4-hydroxy-2-methoxyphenyl)-1-(4-hydroxyphenyl)prop-2-en-1-one::CHEMBL1778898

SMILES COc1cc(O)c(Br)cc1\C=C\C(=O)c1ccc(O)cc1

InChI Key InChIKey=PNFORSNOOCBHAA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344621   

TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Chonnam National University

Curated by ChEMBL
LigandPNGBDBM50344621((E)-3-(5-Bromo-4-hydroxy-2-methoxyphenyl)-1-(4-hyd...)
Affinity DataIC50: 1.37E+4nMAssay Description:Inhibition of recombinant human PTP1B using p-nitrophenyl phosphate as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Shanghai University of Traditional Chinese Medicine

Curated by ChEMBL
LigandPNGBDBM50344621((E)-3-(5-Bromo-4-hydroxy-2-methoxyphenyl)-1-(4-hyd...)
Affinity DataIC50: 1.64E+4nMAssay Description:Inhibition of DPP4 in human plasma using GP-BAN as fluorescent substrate preincubated for 5 mins followed by substrate addition and measured for 20 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed