BDBM50344577 CHEMBL1778454::N-(6-amino-5-fluoro-4-(trifluoromethyl)pyridin-2-ylcarbamoyl)-5-(2-methoxyethyl)-4-methylthiophene-2-sulfonamide

SMILES COCCc1sc(cc1C)S(=O)(=O)NC(=O)Nc1cc(c(F)c(N)n1)C(F)(F)F

InChI Key InChIKey=AUTWHHYCTNKYNS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344577   

TargetFructose-1,6-bisphosphatase 1(Human)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50344577(N-(6-amino-5-fluoro-4-(trifluoromethyl)pyridin-2-y...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human liver fructose-1,6-bisphosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetFructose-1,6-bisphosphatase 1(Mouse)
F. Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50344577(N-(6-amino-5-fluoro-4-(trifluoromethyl)pyridin-2-y...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of mouse liver fructose-1,6-bisphosphataseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed