BDBM50344512 (1R,5R)-isopropyl 3-(5-methyl-6-(2-methylpyridin-3-yloxy)pyrimidin-4-yloxy)-8-azabicyclo[3.2.1]oct-6-ene-8-carboxylate::CHEMBL1778249

SMILES CC(C)OC(=O)N1[C@@H]2CC(C[C@@H]1C=C2)Oc1ncnc(Oc2cccnc2C)c1C

InChI Key

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344512   

TargetGlucose-dependent insulinotropic receptor(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344512((1R,5R)-isopropyl 3-(5-methyl-6-(2-methylpyridin-3...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetGlucose-dependent insulinotropic receptor(Mouse)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50344512((1R,5R)-isopropyl 3-(5-methyl-6-(2-methylpyridin-3...)
Affinity DataEC50:  52nMAssay Description:Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed