BDBM50344446 CHEMBL1699130::dimethyl-4,4'-(ethane-1,2-diylbis(benzylazanediyl))bis(4-oxobutanoate)

SMILES COC(=O)CCC(=O)N(CCN(Cc1ccccc1)C(=O)CCC(=O)OC)Cc1ccccc1

InChI Key InChIKey=JSFZAZDZIONDON-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50344446   

TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344446(dimethyl-4,4'-(ethane-1,2-diylbis(benzylazanediyl)...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetPlasmepsin II(Plasmodium falciparum)
Trinity College

Curated by ChEMBL
LigandPNGBDBM50344446(dimethyl-4,4'-(ethane-1,2-diylbis(benzylazanediyl)...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of Plasmodium falciparum plasmepsin 2 using DABCYL-Glu-Arg-Nle-Phe-Leu- Ser-Phe-Pro-EDANS fluorogenic substrate by fluorogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed