BDBM50344300 (R)-1-(2-phenoxyethyl)-3-(m-tolyl(2,4,5-trifluorobenzyl)carbamoyloxy)-1-azoniabicyclo[2.2.2]octane bromide::CHEMBL1779139

SMILES Cc1cccc(c1)N(Cc1cc(F)c(F)cc1F)C(=O)O[C@H]1C[N+]2(CCOc3ccccc3)CCC1CC2

InChI Key InChIKey=GCRHFBFSDNBRFV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50344300   

TargetMuscarinic acetylcholine receptor M3(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50344300((R)-1-(2-phenoxyethyl)-3-(m-tolyl(2,4,5-trifluorob...)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [3H]NMS from human muscarinic M3 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50344300((R)-1-(2-phenoxyethyl)-3-(m-tolyl(2,4,5-trifluorob...)
Affinity DataIC50: 28nMAssay Description:Displacement of [3H]NMS from human muscarinic M2 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50344300((R)-1-(2-phenoxyethyl)-3-(m-tolyl(2,4,5-trifluorob...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of [3H]NMS from human muscarinic M1 receptor expressed in CHO-K1 cells after 1 hr by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed