BDBM50344133 CHEMBL1778103::N-(6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrimidin-3-yl)benzenesulfonamide

SMILES Fc1ccc(Oc2ncc3c(NS(=O)(=O)c4ccccc4)[nH]nc3n2)c(F)c1

InChI Key InChIKey=GYKPBXNKYPWCBR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344133   

TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344133(N-(6-(2,4-difluorophenoxy)-1H-pyrazolo[3,4-d]pyrim...)
Affinity DataIC50: 257nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed