BDBM50344131 6-(2,4-difluorophenoxy)-N-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-3-amine::CHEMBL1778105

SMILES CC(C)Nc1[nH]nc2nc(Oc3ccc(F)cc3F)ncc12

InChI Key InChIKey=AIMLQKVGYXQMSZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50344131   

TargetMitogen-activated protein kinase 14(Human)
Roche Palo Alto

Curated by ChEMBL
LigandPNGBDBM50344131(6-(2,4-difluorophenoxy)-N-isopropyl-1H-pyrazolo[3,...)
Affinity DataIC50: 23nMAssay Description:Inhibition of p38alpha assessed as [33P]gamma-ATP incorporation into myelin basic proteinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed