BDBM50343990 CHEMBL1779803::N-(2-(5-fluorobenzo[b]thiophen-3-yl)ethyl)acetamide

SMILES CC(=O)NCCc1csc2ccc(F)cc12

InChI Key InChIKey=BGEUHXQJMMIBOC-UHFFFAOYSA-N

Data  2 KI  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50343990   

TargetMelatonin receptor type 1A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50343990(N-(2-(5-fluorobenzo[b]thiophen-3-yl)ethyl)acetamid...)
Affinity DataEC50:  23.8nMAssay Description:Agonist activity at human MT1 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50343990(N-(2-(5-fluorobenzo[b]thiophen-3-yl)ethyl)acetamid...)
Affinity DataEC50:  0.680nMAssay Description:Agonist activity at human MT2 receptor expressed in CHO cells by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1B(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50343990(N-(2-(5-fluorobenzo[b]thiophen-3-yl)ethyl)acetamid...)
Affinity DataKi:  4.87nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMelatonin receptor type 1A(Human)
University of Lille

Curated by ChEMBL
LigandPNGBDBM50343990(N-(2-(5-fluorobenzo[b]thiophen-3-yl)ethyl)acetamid...)
Affinity DataKi:  24.6nMAssay Description:Displacement of 2-[125I]iodomelatonin from human MT1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed