BDBM50343719 CHEMBL1774041::methyl 3-(4-(5-(4-methoxyphenyl)-4-p-tolylpyrimidine-2-carbonyl)piperazin-1-yl)-1-naphthoate

SMILES COC(=O)c1cc(cc2ccccc12)N1CCN(CC1)C(=O)c1ncc(-c2ccc(OC)cc2)c(n1)-c1ccc(C)cc1

InChI Key InChIKey=PONUVWVWQZXJIX-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343719   

TargetCholecystokinin receptor type A(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50343719(methyl 3-(4-(5-(4-methoxyphenyl)-4-p-tolylpyrimidi...)
Affinity DataEC50:  9.60nMAssay Description:Agonist activity at human CCK1 receptor expressed in CHO Flip cells assessed as increase of radio labeled inositol phosphate accumulation by Wallac m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCholecystokinin receptor type A(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50343719(methyl 3-(4-(5-(4-methoxyphenyl)-4-p-tolylpyrimidi...)
Affinity DataIC50: 4.70nMAssay Description:Displacement of [I125]-CCK8 from human CCK1 receptor expressed in CHO Flip cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed