BDBM50343428 1-(2-Chloro-2-phenylethyl)-N-(4-fluorobenzyl)-6-[(2-morpholin-4-ylethyl)thio]-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL1775038

SMILES Fc1ccc(CNc2nc(SCCN3CCOCC3)nc3n(CC(Cl)c4ccccc4)ncc23)cc1

InChI Key InChIKey=CPDSRMMNSWFLRF-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50343428   

TargetTyrosine-protein kinase ABL1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50343428(1-(2-Chloro-2-phenylethyl)-N-(4-fluorobenzyl)-6-[(...)
Affinity DataKi:  580nMAssay Description:Inhibition of human recombinant c-Abl by filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50343428(1-(2-Chloro-2-phenylethyl)-N-(4-fluorobenzyl)-6-[(...)
Affinity DataKi:  580nMAssay Description:Inhibition of AblMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50343428(1-(2-Chloro-2-phenylethyl)-N-(4-fluorobenzyl)-6-[(...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human recombinant c-Src by filter-binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50343428(1-(2-Chloro-2-phenylethyl)-N-(4-fluorobenzyl)-6-[(...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of c-SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Fyn(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50343428(1-(2-Chloro-2-phenylethyl)-N-(4-fluorobenzyl)-6-[(...)
Affinity DataKi:  1.55E+4nMAssay Description:Inhibition of human recombinant full-length Fyn using Src substrate peptide after 15 mins incubation by MicroBeta liquid scintillation counting analy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/9/2016
Entry Details Article
PubMed