BDBM50343388 7-((2-fluorophenyl)(4-methylpyridin-2-ylamino)methyl)quinolin-8-ol::CHEMBL589912

SMILES Cc1ccnc(NC(c2ccccc2F)c2ccc3cccnc3c2O)c1

InChI Key InChIKey=LLJNUTJAVMTITA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343388   

TargetUracil-DNA glycosylase(VACV)
University of Pennsylvania

Curated by ChEMBL
LigandPNGBDBM50343388(7-((2-fluorophenyl)(4-methylpyridin-2-ylamino)meth...)
Affinity DataIC50: 1.57E+5nMAssay Description:Inhibition of Vaccinia virus WR strain processivity factor D4 interaction with A20 protein assessed as inhibition of E9 DNA polymerase-mediated DIG-d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetProtein disulfide-isomerase(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50343388(7-((2-fluorophenyl)(4-methylpyridin-2-ylamino)meth...)
Affinity DataIC50: 880nMAssay Description:Inhibition of recombinant human wild-type N-terminal His-tagged PDIA1 expressed in Escherichia coli strain BL21(DE3) using bovine insulin as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2022
Entry Details Article
PubMed