BDBM50343149 CHEMBL1773182::N1-(2-(1H-indol-3-yl)ethyl)-N2-(1-(4-(4-fluorophenyl)piperazin-1-yl)-1-(thiophen-2-yl)propan-2-yl)oxalamide

SMILES CC(NC(=O)C(=O)NCCc1c[nH]c2ccccc12)C(N1CCN(CC1)c1ccc(F)cc1)c1cccs1

InChI Key InChIKey=QVPQOJFJSHPFCK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343149   

TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343149(N1-(2-(1H-indol-3-yl)ethyl)-N2-(1-(4-(4-fluorophen...)
Affinity DataIC50: 1.75E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB preincubated with compound for 30 mins before pNPP substrate addition by micropl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343149(N1-(2-(1H-indol-3-yl)ethyl)-N2-(1-(4-(4-fluorophen...)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed