BDBM50343144 CHEMBL1773170::N-(3-chloro-4-hydroxynaphthalen-1-yl)-2-oxo-1,2-dihydrobenzo[cd]indole-6-sulfonamide

SMILES Oc1c(Cl)cc(NS(=O)(=O)c2ccc3NC(=O)c4cccc2c34)c2ccccc12

InChI Key InChIKey=PWVPVPJXCKMXDA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343144   

TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343144(N-(3-chloro-4-hydroxynaphthalen-1-yl)-2-oxo-1,2-di...)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPB preincubated with compound for 30 mins before pNPP substrate addition by micropl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Indiana University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50343144(N-(3-chloro-4-hydroxynaphthalen-1-yl)-2-oxo-1,2-di...)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis N-terminal His6-tagged PTPBMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/6/2013
Entry Details Article
PubMed