BDBM50343140 CHEMBL1770314::Neocyclomorusin

SMILES CC(C)(O)C1Cc2c(oc3c4C=CC(C)(C)Oc4cc(O)c3c2=O)-c2ccc(O)cc2O1

InChI Key InChIKey=BKIVBOLDWRIFMA-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50343140   

TargetBeta-secretase 1(Human)
Gyeongsang National University

Curated by ChEMBL
LigandPNGBDBM50343140(Neocyclomorusin | CHEMBL1770314)
Affinity DataIC50: 1.46E+5nMAssay Description:Inhibition of human recombinant BACE-1 expressed in HEK293 cells assessed as inhibition of amyloid precursor protein cleavage into amyloid beta after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCholinesterase(Human)TBA
LigandPNGBDBM50343140(Neocyclomorusin | CHEMBL1770314)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article

TargetAcetylcholinesterase(Human)TBA
LigandPNGBDBM50343140(Neocyclomorusin | CHEMBL1770314)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of AChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article