BDBM50343130 CHEMBL1771458::N-(3-ethylphenyl)-2-(pyrimidin-5-yl)-4-o-tolyl-7,8-dihydropyrido[4,3-d]pyrimidine-6(5H)-carboxamide

SMILES CCc1cccc(NC(=O)N2CCc3nc(nc(c3C2)-c2ccccc2C)-c2cncnc2)c1

InChI Key InChIKey=WBFZANJQMLFGOG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50343130   

TargetP2Y purinoceptor 14(Mouse)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343130(N-(3-ethylphenyl)-2-(pyrimidin-5-yl)-4-o-tolyl-7,8...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at mouse P2Y14 expressed in human HEK cells coexpressing Galphai5 assessed as inhibition of UDP-glucose stimulated calcium releas...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Frosst Center For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50343130(N-(3-ethylphenyl)-2-(pyrimidin-5-yl)-4-o-tolyl-7,8...)
Affinity DataIC50: 5.00E+3nMAssay Description:Displacement of [35S]MK-0499 from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed