BDBM50343082 CHEMBL1771217::N-hydroxy-4-(4-(3-(5-(5-methylpyridin-2-yl)-2H-tetrazol-2-yl)propoxy)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide

SMILES Cc1ccc(nc1)-c1nnn(CCCOc2ccc(cc2)S(=O)(=O)C2(CCOCC2)C(=O)NO)n1

InChI Key InChIKey=MMCUCOOPEAHRPL-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50343082   

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(N-hydroxy-4-(4-(3-(5-(5-methylpyridin-2-yl)-2H-tet...)
Affinity DataKi:  0.660nMAssay Description:Inhibition of human MMP-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(N-hydroxy-4-(4-(3-(5-(5-methylpyridin-2-yl)-2H-tet...)
Affinity DataKi:  44nMAssay Description:Inhibition of human MMP-3More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(N-hydroxy-4-(4-(3-(5-(5-methylpyridin-2-yl)-2H-tet...)
Affinity DataKi:  110nMAssay Description:Inhibition of human MMP-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(N-hydroxy-4-(4-(3-(5-(5-methylpyridin-2-yl)-2H-tet...)
Affinity DataKi:  240nMAssay Description:Inhibition of human MMP-8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(N-hydroxy-4-(4-(3-(5-(5-methylpyridin-2-yl)-2H-tet...)
Affinity DataKi:  2.40E+3nMAssay Description:Inhibition of human MMP-9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMatrilysin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(N-hydroxy-4-(4-(3-(5-(5-methylpyridin-2-yl)-2H-tet...)
Affinity DataKi:  3.00E+3nMAssay Description:Inhibition of human MMP-7More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(N-hydroxy-4-(4-(3-(5-(5-methylpyridin-2-yl)-2H-tet...)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of human MMP-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343082(N-hydroxy-4-(4-(3-(5-(5-methylpyridin-2-yl)-2H-tet...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of human MMP-14More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed