BDBM50343064 CHEMBL1770710::N-hydroxy-4-(4-(4-oxo-4-(piperidin-1-yl)butoxy)phenylsulfonyl)tetrahydro-2H-pyran-4-carboxamide

SMILES ONC(=O)C1(CCOCC1)S(=O)(=O)c1ccc(OCCCC(=O)N2CCCCC2)cc1

InChI Key InChIKey=DZVDZJSJBKHJOK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50343064   

TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343064(N-hydroxy-4-(4-(4-oxo-4-(piperidin-1-yl)butoxy)phe...)
Affinity DataIC50: 670nMAssay Description:Inhibition of human MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343064(N-hydroxy-4-(4-(4-oxo-4-(piperidin-1-yl)butoxy)phe...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343064(N-hydroxy-4-(4-(4-oxo-4-(piperidin-1-yl)butoxy)phe...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343064(N-hydroxy-4-(4-(4-oxo-4-(piperidin-1-yl)butoxy)phe...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed