BDBM50343056 4-(4-(3-(cyclohexanecarboxamido)propoxy)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide::CHEMBL1770704

SMILES ONC(=O)C1(CCOCC1)S(=O)(=O)c1ccc(OCCCNC(=O)C2CCCCC2)cc1

InChI Key InChIKey=UKBSDNIYHDAZDN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50343056   

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343056(4-(4-(3-(cyclohexanecarboxamido)propoxy)phenylsulf...)
Affinity DataIC50: 650nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343056(4-(4-(3-(cyclohexanecarboxamido)propoxy)phenylsulf...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343056(4-(4-(3-(cyclohexanecarboxamido)propoxy)phenylsulf...)
Affinity DataIC50: 8.20nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed