BDBM50343055 4-(4-(3-(2,4-dimethylbenzamido)propoxy)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide::CHEMBL1770703

SMILES Cc1ccc(C(=O)NCCCOc2ccc(cc2)S(=O)(=O)C2(CCOCC2)C(=O)NO)c(C)c1

InChI Key InChIKey=KLRCKSDGEDNMNL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50343055   

Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343055(4-(4-(3-(2,4-dimethylbenzamido)propoxy)phenylsulfo...)
Affinity DataIC50: 940nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343055(4-(4-(3-(2,4-dimethylbenzamido)propoxy)phenylsulfo...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343055(4-(4-(3-(2,4-dimethylbenzamido)propoxy)phenylsulfo...)
Affinity DataIC50: 8nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed