BDBM50343051 4-(4-(5-(4-(dimethylamino)phenyl)-5-oxopentyloxy)phenylsulfonyl)-N-hydroxytetrahydro-2H-pyran-4-carboxamide::CHEMBL1770699

SMILES CN(C)c1ccc(cc1)C(=O)CCCCOc1ccc(cc1)S(=O)(=O)C1(CCOCC1)C(=O)NO

InChI Key InChIKey=WBIKMXRYXWFRCE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50343051   

TargetMatrix metalloproteinase-9(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343051(4-(4-(5-(4-(dimethylamino)phenyl)-5-oxopentyloxy)p...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human MMP9More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343051(4-(4-(5-(4-(dimethylamino)phenyl)-5-oxopentyloxy)p...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human MMP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343051(4-(4-(5-(4-(dimethylamino)phenyl)-5-oxopentyloxy)p...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human MMP8More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50343051(4-(4-(5-(4-(dimethylamino)phenyl)-5-oxopentyloxy)p...)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human MMP13More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed