BDBM50342852 1,1'-[Biphenyl-3,3'-diylbis(methylene)]bis(quinuclidinium)bromide::CHEMBL1771549

SMILES C(c1cccc(c1)-c1cccc(C[N+]23CCC(CC2)CC3)c1)[N+]12CCC(CC1)CC2

InChI Key InChIKey=UIHMPKAPVFKAFT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50342852   

TargetAcetylcholinesterase(Human)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50342852(1,1'-[Biphenyl-3,3'-diylbis(methylene)]bis(quinucl...)
Affinity DataIC50: 620nMAssay Description:Inhibition of human recombinant AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCholinesterase(Human)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50342852(1,1'-[Biphenyl-3,3'-diylbis(methylene)]bis(quinucl...)
Affinity DataIC50: 36nMAssay Description:Inhibition of human BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetAcetylcholinesterase(Bovine)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50342852(1,1'-[Biphenyl-3,3'-diylbis(methylene)]bis(quinucl...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of bovine AChE after 20 mins using acetylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
Universidad De Granada

Curated by ChEMBL
LigandPNGBDBM50342852(1,1'-[Biphenyl-3,3'-diylbis(methylene)]bis(quinucl...)
Affinity DataIC50: 89nMAssay Description:Inhibition of equine BChE after 20 mins using butyrylthiocholine iodide as a substrate by Ellman's assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed