BDBM50342741 3-Cyano-4-(1-naphthyl)-N-(1-[2-chlorophenyl]-3-phenyl-1H-pyrazol-5-yl)benzamide::CHEMBL1771274

SMILES Clc1ccccc1-n1nc(cc1NC(=O)c1ccc(c(c1)C#N)-c1cccc2ccccc12)-c1ccccc1

InChI Key InChIKey=QXMHSRQAHOLIQB-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342741   

TargetMetabotropic glutamate receptor 5(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50342741(3-Cyano-4-(1-naphthyl)-N-(1-[2-chlorophenyl]-3-phe...)
Affinity DataEC50:  2.17E+3nMAssay Description:Agonist activity at rat mGluR5 expressed in HEK293T cells assessed as effect on glutamate-induced calcium flux by calcium fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Rat)
National Institute On Drug Abuse-Intramural Research Program

Curated by ChEMBL
LigandPNGBDBM50342741(3-Cyano-4-(1-naphthyl)-N-(1-[2-chlorophenyl]-3-phe...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-MPEP from mGluR5 in rat brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed