BDBM50342713 3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl]-6-phenylisoquinolin-1(2H)-one::CHEMBL1771107

SMILES COc1ccccc1N1CCN(CCCCN2CCc3cc(ccc3C2=O)-c2ccccc2)CC1

InChI Key InChIKey=UTEITPSYNTYGQL-UHFFFAOYSA-N

Data  5 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50342713   

TargetD(3) dopamine receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50342713(3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-y...)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at human dopamine D3 receptor expressed in dhfr-deficient CHO cells assessed as [3H]thymidine incorporationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50342713(3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-y...)
Affinity DataKi:  0.25nMAssay Description:Displacement of [3H]Spiperone from human dopamine D3 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50342713(3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-y...)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2 short receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50342713(3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-y...)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]Spiperone from human dopamine D2 long receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Pig)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50342713(3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-y...)
Affinity DataKi:  330nMAssay Description:Displacement of [3H]Ketanserin from pig 5-HT2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetD(1A) dopamine receptor(Pig)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50342713(3,4-Dihydro-2-[4-(4-(2-methoxyphenyl)piperazin-1-y...)
Affinity DataKi:  640nMAssay Description:Displacement of [3H]SCH-23390 from dopamine D1 receptor in pig striatal membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed