BDBM50342589 (E)-4-chloro-1-isobutyl-3-(2-oxo-2-(pyridin-3-yl)ethylidene)indolin-2-one::CHEMBL1770528

SMILES CC(C)CN1C(=O)\C(=C\C(=O)c2cccnc2)c2c1cccc2Cl

InChI Key InChIKey=CLXODGSVTJDZTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342589   

TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342589((E)-4-chloro-1-isobutyl-3-(2-oxo-2-(pyridin-3-yl)e...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342589((E)-4-chloro-1-isobutyl-3-(2-oxo-2-(pyridin-3-yl)e...)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed