BDBM50342587 (E)-3-(2-(4-aminophenyl)-2-oxoethylidene)-4-chloroindolin-2-one::CHEMBL1770525

SMILES Nc1ccc(cc1)C(=O)\C=C1\C(=O)Nc2cccc(Cl)c12

InChI Key InChIKey=YPCDUPVKTJDCGO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342587   

TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342587((E)-3-(2-(4-aminophenyl)-2-oxoethylidene)-4-chloro...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342587((E)-3-(2-(4-aminophenyl)-2-oxoethylidene)-4-chloro...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed