BDBM50342581 (E)-4-chloro-3-(2-(3-chlorophenyl)-2-oxoethylidene)indolin-2-one::CHEMBL1770519

SMILES Clc1cccc(c1)C(=O)\C=C1\C(=O)Nc2cccc(Cl)c12

InChI Key InChIKey=KCLKBEHIPYSRFL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342581   

TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342581((E)-4-chloro-3-(2-(3-chlorophenyl)-2-oxoethylidene...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human transglutaminase 2 using Cbz-Gln-Gly as a substrate by GDH-coupled assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProtein-glutamine gamma-glutamyltransferase 2(Human)
Stanford University

Curated by ChEMBL
LigandPNGBDBM50342581((E)-4-chloro-3-(2-(3-chlorophenyl)-2-oxoethylidene...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human transglutaminase 2 using ZGBC as a substrate after 30 to 60 mins by fluorometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed