BDBM50342545 2-(2-chlorobenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[5,4-d]azepine::CHEMBL1770381

SMILES Clc1ccccc1Cc1ncc2CCNCCc2n1

InChI Key InChIKey=MZFWITNMUUIKAS-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50342545   

Target5-hydroxytryptamine receptor 2B(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342545(2-(2-chlorobenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[...)
Affinity DataEC50:  178nMAssay Description:Agonist activity at human 5HT2B receptor expressed in CHO-K1 cells assessed as increase of fluorescence based calcium mobilization by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50342545(2-(2-chlorobenzyl)-6,7,8,9-tetrahydro-5H-pyrimido[...)
Affinity DataKi:  1.85E+3nMAssay Description:Displacement of [3H]meselurgine from human 5HT2C receptor expressed in Swiss mouse 3T3 cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed