BDBM50342486 5-chloro-N-(4-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)phenyl)-4-(1-methyl-1H-pyrazol-3-yl)pyridin-2-amine::CHEMBL1771663

SMILES Cc1nc(C)n(n1)-c1ccc(Nc2cc(-c3ccn(C)n3)c(Cl)cn2)cc1

InChI Key InChIKey=RPLUSWNGTMKDQG-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342486   

TargetMitogen-activated protein kinase 10(Human)
The Scripps Research Institute

Curated by ChEMBL
LigandPNGBDBM50342486(5-chloro-N-(4-(3,5-dimethyl-1H-1,2,4-triazol-1-yl)...)
Affinity DataIC50: 160nMAssay Description:Inhibition of JNK3 assessed as formation of phospho-Thr71-ATF-2 from biotinylated-ATF2 by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed