BDBM50342476 (S)-cyclobutyl(3-(3-(3-methoxyphenyl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)methanone::CHEMBL1771623

SMILES COc1cccc(c1)-c1noc(n1)[C@H]1CCCN(C1)C(=O)C1CCC1

InChI Key InChIKey=KIVCLWIXIFBBDX-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50342476   

TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50342476((S)-cyclobutyl(3-(3-(3-methoxyphenyl)-1,2,4-oxadia...)
Affinity DataIC50: 1.80E+3nMAssay Description:Negative allosteric modulator activity at mGluR5 receptor expressed in HEK293A cells assessed as inhibition of glutamate-induced calcium flux preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed